Photo by Geraldine Soh

Hotels near Historic Main Street

Free cancellation options if plans change
Unlock travel rewards with One Key
Save more with Member Prices

Check prices for these dates

Tonight
11 May - 12 May
Tomorrow
12 May - 13 May
Next weekend
16 May - 18 May
In two weeks
23 May - 25 May

Where to stay near Historic Main Street?

Ameristar Casino Resort and Spa
Casino

Ameristar Casino Resort and Spa

4.5 star property
8.4 out of 10, Very good, (1006)
The price is £161
includes taxes & fees
21 May - 22 May
Ameristar Casino Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other landmarks in St. Charles Historic District

First Missouri State Capitol Historic Site

You can learn about the history of St. Charles with a stop at First Missouri State Capitol Historic Site. Discover the top-notch restaurants and acclaimed theatre scene in this family-friendly area.

See properties in First Missouri State Capitol Historic Site
First Missouri State Capitol Historic Site
A tranquil hotel pool encircled by beautiful arches

Summer Getaway Sale

Sign in to save 25%+ on selected hotels, and earn 50% more rewards on all properties. Book by 26 May and travel by 30 Sep 2025. See terms*
Sign in or join for free

Frequently asked questions

What are the best hotels near Historic Main Street?
How much does it cost to stay in a hotel near Historic Main Street?
On Hotels.com, you can find a variety of room prices depending on when and where you plan to go. Take a look at what’s available during your travel dates, sort by price, and filter by your criteria to find the best option within your travel budget.
  • Search for the lowest price per night £73
What cheap hotels are close to Historic Main Street?
Can I find hotels close to Historic Main Street that are fully refundable?
Yes, many hotels offer refundable room reservations if you cancel prior to the cancellation deadline. To find refundable rates, select the “Fully refundable” filter when searching for hotels.
What are the best hotels close to Historic Main Street with free breakfast?
What are the best family hotels close to Historic Main Street?
What are the best luxury hotels near Historic Main Street?
  • Pamper yourself with a stay at Ameristar Casino Resort and Spa, which is a 11-minute walk from Historic Main Street. This hotel features 6 restaurants including Bugattis Steak and Pasta and has a full-service spa.
  • Another luxurious option is The Ritz-Carlton, St. Louis, which is 23 minutes away by car.
What are the best hotels near Historic Main Street with free parking?
What are the best hotels near Historic Main Street with a pool?
What cheap motels can I book close to Historic Main Street?
What are the best things to see and do around my hotel near Historic Main Street?
  • Before or after your visit to Historic Main Street, you can check out top attractions like St. Louis Zoo, Enterprise Center, and Busch Stadium.
  • Gateway Arch is another popular place in the area.

Terms and conditions

*Book by 26/5/2025 11:59pm in hotel property local time. Stay between 17/4/2025–30/9/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

One Key members save more, as compared to non-members shopping on Hotels.com. OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia® and Vrbo®.