Hotels in Santa Ana

Search for Santa Ana Hotels

Hotels.com™ Rewards

Collect 10 nights, get 1 reward night

And look out for Secret Prices on selected hotels

  • Pay now or later on most rooms
  • Free cancellation on most rooms
  • Price Guarantee

Best Santa Ana Hotels

Santa Ana overview

Santa Ana is known for its historical sites. Learn about local heritage at landmarks, such as Nuestra Senora de Santa Ana and San Ignacio Mini. A stop at places like Casa de Horacio Quiroga and San Ignacio Miní will create some memories. Santa Ana is an inviting destination that has something for everyone.

Where to stay in Santa Ana

Whether you're planning to stay for a night or for the week, the area around Santa Ana has accommodations to fit every need. Search for hotels in Santa Ana with Hotels.com by checking our online maps. These display the areas and neighbourhoods around all Santa Ana hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Santa Ana hotel deals are here with our lowest price guarantee.

How to get to Santa Ana

Fly in to Posadas (PSS-Libertador General Jose de San Martin), 24.4 mi (39.2 km) from central Santa Ana.

What to see around Santa Ana

Acclaimed for its historical sites, here are some top landmarks to visit:
  • • Nuestra Senora de Santa Ana
  • • San Ignacio Mini
  • • San Ignacio Miní
  • • Horacio Quiroga Home
  • • San Ignacio Mini - Jesuit Missions of the Guaranis
Some highlights of the area include:
  • • Casa de Horacio Quiroga
  • • Museu Horacio Quiroga
  • • Former House of Stroessner
  • • La Santisima Trinidad de Parana
  • • Plaza de Armas

When to visit Santa Ana

Wondering when the best time to visit is? Here are seasonal trends to help you plan your trip:

Seasonal temperatures
  • January-March: 32°C day, 18°C night
  • April-June: 29°C day, 10°C night
  • July-September: 26°C day, 10°C night
  • October-December: 32°C day, 15°C night
Seasonal average rainfall
  • January-March: 438 cm
  • April-June: 439 cm
  • July-September: 325 cm
  • October-December: 429 cm
  • Historical sites