Hotels in Medicine Lake

Free cancellation options if plans change
Unlock travel rewards with One Key
Save more with Member Prices

Check prices for these dates

Tonight
22 May - 23 May
Tomorrow
23 May - 24 May
This weekend
23 May - 25 May
Next weekend
30 May - 1 Jun

Where to stay in Medicine Lake?

Top landmarks in Medicine Lake

Medicine Lake National Wildlife Refuge

Commune with nature and explore the great outdoors at Medicine Lake National Wildlife Refuge during your travels in Medicine Lake.

See properties in Medicine Lake National Wildlife Refuge
Medicine Lake National Wildlife Refuge

Learn more about Medicine Lake

The region around Medicine Lake is home to attractions such as Medicine Lake National Wildlife Refuge and Big Island.

See all hotels in Medicine Lake
A tranquil hotel pool encircled by beautiful arches

Summer Getaway Sale

Sign in to save 25%+ on selected hotels, and earn 50% more rewards on all properties. Book by 26 May and travel by 30 Sep 2025. See terms*
Sign in or join for free

Frequently asked questions

What hotels do travellers recommend in Medicine Lake?
Guests like Newly remodeled home minutes from Medicine Lake NWR..
Can I book a refundable accommodation option in Medicine Lake?
If you want the flexibility to change your plans to Medicine Lake, most hotels offer refundable* rates that you can book. You can see these properties by searching our site and using the “fully refundable” filter to narrow down the results.
What will the weather in Medicine Lake be like during my visit?
July and August are typically the warmest months in Medicine Lake, when the average temperature is 19°C. February and January are the coldest months, when the average temperature is -8°C. June and May are the months with the most rain.
Why should I book my Medicine Lake hotel with Hotels.com?
There are lots of reasons to book your Medicine Lake trip with us: our free cancellations on selected hotels* gives you flexibility, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.

Terms and conditions

*Book by 26/5/2025 11:59pm in hotel property local time. Stay between 17/4/2025–30/9/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

One Key members save more, as compared to non-members shopping on Hotels.com. OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia® and Vrbo®.