Hotels in La Mesa

Free cancellation options if plans change
Unlock travel rewards with One Key
Save more with Member Prices

Check prices for these dates

Tonight
15 May - 16 May
Tomorrow
16 May - 17 May
This weekend
16 May - 18 May
Next weekend
23 May - 25 May

Where to stay in La Mesa?

B&B Lodgings
Laptop workspace, soundproofing, free WiFi, bed sheets

B&B Lodgings

2.5 star property
7.8 out of 10, Good, (67)
The price is £40
includes taxes & fees
17 May - 18 May
B&B Lodgings
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in La Mesa

Honeycreeper Ridge Trail

Honeycreeper Ridge Trail is 5.1 mi (8.2 km) from central San Martín, why not stop by during your stay?

See properties in Honeycreeper Ridge Trail
Honeycreeper Ridge Trail

Learn more about La Mesa

The region around La Mesa is home to attractions such as Metromall Panama and Los Pueblos Commercial Center.

See all hotels in La Mesa

Check out reviews of La Mesa hotels guests love

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

10/10 Excellent
"Expensive but very nice"
ANA 1-night trip
Posted 16 hours ago
Riande Aeropuerto Hotel & Casino
A tranquil hotel pool encircled by beautiful arches

Summer Getaway Sale

Sign in to save 25%+ on selected hotels, and earn 50% more rewards on all properties. Book by 26 May and travel by 30 Sep 2025. See terms*
Sign in or join for free

Frequently asked questions

What hotels do travellers recommend in La Mesa?
Guests like Crowne Plaza Panama Airport by IHG, Express Inn Panama International Airport Hostel and B&B Lodgings.
Can I book a refundable accommodation option in La Mesa?
If you want the flexibility to change your plans to La Mesa, most hotels offer refundable* rates that you can book. You can find this accommodation by searching our site and using the “fully refundable” filter to narrow down the results.
What will the weather in La Mesa be like during my visit?
With an average temperature of 26°C during the coldest months, La Mesa is a great place to visit at any time of year.
Why should I book my La Mesa hotel with Hotels.com?
There are plenty of reasons to book your La Mesa travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.

Terms and conditions

*Book by 26/5/2025 11:59pm in hotel property local time. Stay between 17/4/2025–30/9/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

One Key members save more, as compared to non-members shopping on Hotels.com. OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia® and Vrbo®.