Hotels in Southern Indiana

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Where to stay in Southern Indiana?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southern Indiana

Showing deals for:2 May - 4 May

Top neighbourhoods in Southern Indiana

Top landmarks in Southern Indiana

Learn more about Southern Indiana

Southern Indiana is applauded for its live music and entertainment with such cultural attractions as French Lick Scenic Railway and Santa Claus Museum. The city has something for everyone including its casinos, restaurants, and sights like Patoka Lake and Sultan's Run Golf Course.

Kentucky Center for the Performing Arts which includes modern architecture
A tranquil hotel pool encircled by beautiful arches

Summer Getaway Sale

Sign in to save 25%+ on selected hotels, and earn 50% more rewards on all properties. Book by 26 May and travel by 30 Sep 2025. See terms*

Frequently asked questions

What hotels do travellers recommend in Southern Indiana?
The Destination B&B, Hilton Garden Inn Jeffersonville and The Pepin Mansion Historic B&B are all properties that our guests really like.
Can I book a refundable accommodation option in Southern Indiana?
If you want the flexibility to change your plans to Southern Indiana, most hotels offer refundable* rates that you can book. You can find this accommodation by searching our site and using the “fully refundable” filter to narrow the results down.
Which Southern Indiana hotels do travellers like for their great location?
Our guests rave about the location of these properties: Galt House Hotel Trademark Collection by Wyndham, Omni Louisville Hotel and Holiday Inn Express & Suites Louisville Downtown, an IHG Hotel.
Where can I stay in Southern Indiana if I want a holiday rental instead of a hotel?
If you’re looking for a good alternative to a hotel, look over our selection of 328 holiday homes. In addition, there are 185 apartments and 47 condos.
Why should I book my Southern Indiana hotel with Hotels.com?
There are plenty of reasons to book your Southern Indiana travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.

Terms and conditions

*Book by 26/5/2025 11:59pm in hotel property local time. Stay between 17/4/2025–30/9/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

One Key members save more, as compared to non-members shopping on Hotels.com. OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia® and Vrbo®.