Hotels in Upstate South Carolina

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Tonight
19 May - 20 May
Tomorrow
20 May - 21 May
This weekend
23 May - 25 May
Next weekend
30 May - 1 Jun

Where to stay in Upstate South Carolina?

Sleep Inn
Lobby

Sleep Inn

2.5 star property
5.8 out of 10, (479)
The price is £55
includes taxes & fees
26 May - 27 May
Sleep Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Upstate South Carolina, SC

Showing deals for:30 May - 1 Jun

Image gallery for Cambria Hotel Greenville

Property amenity

Cambria Hotel Greenville

3.0 star property
Greenville
9.4/10Exceptional (1,037 reviews)
15% off
Price is £217
£108 per night
includes taxes & fees
Cambria Hotel Greenville

Top neighbourhoods in Upstate South Carolina

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Green Avenue

The Green Avenue neighbourhood offers attractions, such as Falls Park on the Reedy and Greenville Zoo.

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Green Avenue

Top landmarks in Upstate South Carolina

Clemson University

Clemson University

If you'd like to get a taste of Clemson student life, check out Clemson University, located 0.5 mi (0.9 km) from central Clemson.

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Clemson University

Learn more about Upstate South Carolina

Upstate South Carolina is applauded for its cultural attractions such as Heritage Park and Roper Mountain Science Center.

See all hotels in Upstate South Carolina
Greenville - Spartanburg which includes views, tranquil scenes and mountains
Photo by South Carolina Department of Parks, Recreation & Tourism
Open Photo by South Carolina Department of Parks, Recreation & Tourism

Check out reviews of Upstate South Carolina hotels guests love

Hyatt Place Greenville/Downtown

Hyatt Place Greenville/Downtown

10/10 Excellent
"It needed a microwave. Other than that it was great!"
Carisa 1-night trip
Posted 21 hours ago
Hyatt Place Greenville/Downtown
A tranquil hotel pool encircled by beautiful arches

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Frequently asked questions

What hotels do travellers recommend in Upstate South Carolina?
Pettigru Place Bed & Breakfast, The Inn at Patrick Square and Residence Inn by Marriott Anderson Clemson are all properties that our guests really like.
Can I book a refundable accommodation option in Upstate South Carolina?
If you want the flexibility to change your plans to Upstate South Carolina, most hotels offer refundable* rates that you can book. You can find these properties by searching our site and using the “fully refundable” filter to narrow the results down.
Which Upstate South Carolina hotels do travellers like for their great location?
Our guests love these properties for their convenient location: Best Western Plus Greenville I-385 Inn & Suites, La Quinta Inn & Suites by Wyndham Greenville Haywood and Spartanburg Marriott.
Where can I stay in Upstate South Carolina if I want a holiday rental instead of a hotel?
If you want to find a good alternative to a hotel, browse our selection of 1073 holiday homes. In addition, there are 111 apartments and 92 condos.
Why should I book my Upstate South Carolina hotel with Hotels.com?
There are lots of reasons to book your Upstate South Carolina trip with us: our free cancellations on selected hotels* gives you flexibility, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.

Terms and conditions

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