Hotels in San Cosme y Damian

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Where to stay in San Cosme y Damian?

Top landmarks in San Cosme y Damian

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San Cosme y Damian is well known for its attractions such as Buenaventura Suarez Planetarium and Guarani Jesuit Ruins of San Cosme and San Damián.

A tranquil hotel pool encircled by beautiful arches

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Sign in to save 25%+ on selected hotels, and earn 50% more rewards on all properties. Book by 26 May and travel by 30 Sep 2025. See terms*

Frequently asked questions

Can I book a refundable accommodation option in San Cosme y Damian?
If you want the flexibility to change your plans to San Cosme y Damian, most hotels offer refundable* rates that you can book. You can see these properties by searching our site and using the “fully refundable” filter to narrow down the results.
What will the weather in San Cosme y Damian be like during my visit?
January and February are typically the warmest months in San Cosme y Damian, when the average temperature is 26°C. July and June are the coldest months, when the average temperature is 17°C. October and November are the months with the most rain.
Why should I book my San Cosme y Damian hotel with Hotels.com?
There are plenty of reasons to book your San Cosme y Damian travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.

Terms and conditions

*Book by 26/5/2025 11:59pm in hotel property local time. Stay between 17/4/2025–30/9/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

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