Hotels in Upstate South Carolina

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January 2025

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Where to stay in Upstate South Carolina?

Hilton Greenville
Exterior

Hilton Greenville

3.5 star property
8.0 out of 10, Very good, (1000)
The price is £107
includes taxes & fees
13 Dec - 14 Dec
Hilton Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top neighbourhoods in Upstate South Carolina

Get a lay of the land and find the perfect place to stay
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Green Avenue

The Green Avenue neighbourhood offers attractions, such as Falls Park on the Reedy and Greenville Zoo.

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Green Avenue

Top landmarks in Upstate South Carolina

Clemson University

Clemson University

If you'd like to get a taste of Clemson student life, check out Clemson University, located 0.5 mi (0.9 km) from central Clemson.

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Clemson University

Frequently asked questions

What hotels do travellers recommend in Upstate South Carolina?
Pettigru Place Bed & Breakfast, The Inn at Patrick Square and Residence Inn by Marriott Anderson Clemson are all properties that our guests really like.
Can I book a refundable accommodation option in Upstate South Carolina?
If you want the flexibility to change your plans to Upstate South Carolina, most hotels offer refundable* rates that you can book. You can see these properties by searching our site and using the “fully refundable” filter to narrow the results down.
Which Upstate South Carolina hotels do travellers like for their great location?
Our guests love these properties for their convenient location: Best Western Plus Greenville I-385 Inn & Suites, La Quinta Inn & Suites by Wyndham Greenville Haywood and Hilton Greenville.
Where can I stay in Upstate South Carolina if I want a holiday rental instead of a hotel?
If you’re looking for a good alternative to a hotel, review our selection of 1070 holiday homes. In addition, there are 113 apartments and 89 condos.
Why should I book my Upstate South Carolina hotel with Hotels.com?
There are lots of reasons to book your Upstate South Carolina trip with us: our free cancellations on selected hotels* gives you flexibility, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.