Hotels in Wapello

Tue 18 Nov
Thu 20 Nov
November 2025
17
December 2025

Free cancellation options if plans change

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Check prices for these dates

Tonight
17 Nov - 18 Nov
Tomorrow
18 Nov - 19 Nov
This weekend
21 Nov - 23 Nov
Next weekend
28 Nov - 30 Nov

Where to stay in Wapello?

£64
includes taxes & fees
24 Nov - 25 Nov
AmericInn by Wyndham Mount Pleasant
£61
includes taxes & fees
24 Nov - 25 Nov
Best Western Mt. Pleasant Inn
£57
includes taxes & fees
18 Nov - 19 Nov
Super 8 by Wyndham Mt Pleasant
£78
includes taxes & fees
30 Nov - 1 Dec
Hampton Inn Muscatine
£144
includes taxes & fees
5 Dec - 6 Dec
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
£115
includes taxes & fees
24 Nov - 25 Nov
Hampton Inn & Suites Burlington
£114
includes taxes & fees
30 Nov - 1 Dec
Holiday Inn Express Hotel & Suites Burlington by IHG
£136
includes taxes & fees
18 Nov - 19 Nov
The Catfish Bend Inn & Spa
The Sage Hotel
£63
includes taxes & fees
1 Dec - 2 Dec
Comfort Inn Muscatine near Hwy 61
£47
includes taxes & fees
30 Nov - 1 Dec
AmericInn by Wyndham West Burlington
£71
includes taxes & fees
24 Nov - 25 Nov
Best Western Muscatine / Pearl City Hotel
£111
includes taxes & fees
21 Nov - 22 Nov
Fairfield Inn & Suites by Marriott Burlington
£53
includes taxes & fees
24 Nov - 25 Nov
Quality Inn & Suites
£99
includes taxes & fees
25 Nov - 26 Nov
Evans Holly Grove Inn B&B
£127
includes taxes & fees
18 Nov - 19 Nov
Fun City Resort Hotel
£54
includes taxes & fees
29 Nov - 30 Nov
Super 8 by Wyndham Muscatine
£150
includes taxes & fees
18 Nov - 19 Nov
Idyllic Biggsville Vacation Rental: 10 Mi to River
£200
includes taxes & fees
18 Nov - 19 Nov
Hall Building
£69
includes taxes & fees
24 Nov - 25 Nov
AmericInn by Wyndham Muscatine
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Learn more about Wapello

The region around Wapello is home to attractions such as Mississippi River and Cairo Woods Wildlife Area.

See all hotels in Wapello
The Mississippi River near Hannibal, Missouri, USA

Check out reviews of Wapello hotels guests love

The Catfish Bend Inn & Spa

The Catfish Bend Inn & Spa

10/10 Excellent
"Clean room, friendly staff, pretty quiet. "
Keri 1-night trip
Posted 3 days ago
The Catfish Bend Inn & Spa
AmericInn by Wyndham Mount Pleasant

AmericInn by Wyndham Mount Pleasant

10/10 Excellent
"We loved it all! Clean room, helpful staff, excellent breakfast, easy parking, amazing pool room. The only downside is that the treadmill was out of order. On cold nights, that’s a must for travelers needing to get some exercise in. Otherwise, everything was great!"
Marla 1-night trip
Posted 3 days ago
AmericInn by Wyndham Mount Pleasant
Hampton Inn & Suites Burlington

Hampton Inn & Suites Burlington

10/10 Excellent
"Very nice"
Madison 4-night trip
Posted 6 days ago
Hampton Inn & Suites Burlington
Holiday Inn Express Hotel & Suites Burlington by IHG

Holiday Inn Express Hotel & Suites Burlington by IHG

10/10 Excellent
"Very everyone was very nice and "
Mary 1-night trip
Posted 7 days ago
Holiday Inn Express Hotel & Suites Burlington by IHG
Quality Inn & Suites

Quality Inn & Suites

10/10 Excellent
"Clean, good breakfast, great staff "
Melissa 1-night trip
Posted 7 days ago
Quality Inn & Suites
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

10/10 Excellent
"This hotel was wonderful- staff amazing and accommodating. Very classy place and I would highly recommend to anyone traveling to Muscatine."
Mary 1-night trip
Posted 8 days ago
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
Super 8 by Wyndham Mt Pleasant

Super 8 by Wyndham Mt Pleasant

10/10 Excellent
"Great stay! Room was clean, sheets/towel looked brand new, water pressure and temperature was awesome... mom/female approved HOT water!! Staff was very friendly and helpful! Only stayed one night but would most definitely stay again! Thanks for a great stay!"
Stacy 1-night trip
Posted 9 days ago
Super 8 by Wyndham Mt Pleasant
Fun City Resort Hotel

Fun City Resort Hotel

10/10 Excellent
"Room was great! "
Gail 1-night trip
Posted 13 days ago
Fun City Resort Hotel
Hampton Inn Muscatine

Hampton Inn Muscatine

10/10 Excellent
"Didn't eat breakfast, as there was a soccer tournament and the lobby was full. I didn't try the gym. I visited cause my sister passed away and I was there for her funeral. I will definetly stay there again when I am in Muscatine again. The only thing I didn't like was the elevator was scary. It made a weird sound when going up/down. Otherwise the hotel was clean, beautiful room. The bed was a little hard but wasn't terrible. Check in was easy, the front desk employee was very nice and sympathetic. Her kindness is what makes me want to come stay there when I come back into town. Housekeepers do a wonderful job of making sure the room is clean, I didn't see one speck of dust. "
Robin 2-night trip
Posted 13 days ago
Hampton Inn Muscatine

Frequently asked questions

How much does a hotel room cost in Wapello?
You can choose a great hotel in Wapello from £47 with properties to suit all budgets and needs. If you're looking for an affordable hotel in Wapello that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.
How much does a hotel room cost in Wapello?
You can choose a great hotel in Wapello from £47 with properties to suit all budgets and needs. If you're looking for an affordable hotel in Wapello that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com. If you're a member, don't forget to sign in to your account to unlock more savings.
How can I find deals and earn rewards at Wapello hotels?
Discover great deals on Wapello hotel stays with Hotels.com. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If it's a spontaneous trip, check out our last-minute deals on Wapello hotels.
How can I find deals and earn rewards at Wapello hotels?
Members can save up to 20% on select hotels in Wapello. Plus, Silver, Gold and Platinum members earn extra rewards on VIP Access bookings, making each stay even more rewarding.
Can I book Wapello hotels with free cancellation?
It's easy to book a refundable Wapello hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
Can I book a refundable accommodation option in Wapello?
If you want the flexibility to change your plans to Wapello, most hotels offer refundable* rates that you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Wapello be like during my visit?
July and August are typically the warmest months in Wapello, when the average temperature is 22°C. January and February are the coldest months, when the average temperature is -1°C. June and May are the months with the most rain.
Why should I book my Wapello hotel with Hotels.com?
There are lots of reasons to book your Wapello trip with us: our free cancellations on selected hotels* gives you flexibility, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.

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