The Best 5 Star Hotels deals in Jacksonville
Free cancellation options if plans change
Unlock travel rewards with One Key
Save more with Member Prices
The Best 5 Star Hotels deals in Jacksonville
Azaleana Manor
Azaleana Manor
8.8 out of 10, Excellent, (35)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top neighbourhoods in Jacksonville
Southside
The Southside neighbourhood offers attractions, such as St. Johns Town Center and The Avenues.
Top landmarks in Jacksonville
Mayo Clinic Florida
If Mayo Clinic Florida is what brings you to town, hopefully you'll have a chance to explore more of Jacksonville.
Keep exploring
Keep exploring
- Neighbourhoods
- Landmarks
- Star Rating
- Accommodation Types
- Theme
- Top Cities in United States of America
- More Hotels
- Most popular destinations
- More ways to book
- Hotels in Southside
- Hotels in Downtown Jacksonville
- Hotels in Northside
- Hotels in Arlington
- Hotels in Northwest
- Hotels in Westside
- Hotels in Urban Core
- Hotels in Baymeadows
- Hotels in San Marco
- Hotels in Riverside
- Hotels in Mandarin
- Hotels in Deerwood
- Hotels in Mayport
- Hotels in Avondale
- Hotels in Southpoint
- Hotels in Golden Glades - The Woods
- Hotels in Fort George Island
- Hotels in Fruit Cove
- Hotels in Southbank
- Hotels in Beach Haven
- Hotels near EverBank Stadium
- Hotels near St. Johns Town Center
- Hotels near Mayo Clinic Florida
- Hotels near Jacksonville Cruise Terminal
- Hotels near Jacksonville Naval Air Station
- Hotels near Jacksonville Zoo and Gardens
- Hotels near Mayport Naval Station
- Hotels near University of North Florida
- Hotels near VyStar Veterans Memorial Arena
- Hotels near Jacksonville University
- Hotels near Daily's Place
- Hotels near Florida Theatre
- Hotels near Prime F. Osborn III Convention Center
- Hotels near River City Market Place
- Hotels near Jacksonville Equestrian Center
- Hotels near Times-Union Center for the Performing Arts
- Hotels near HCA Florida Memorial Hospital
- Hotels near The Avenues
- Hotels near Baptist Medical Center Jacksonville
- Hotels near St. Vincent's Medical Center
- Jacksonville Cheap Hotels
- Jacksonville Hotels with Parking
- Jacksonville Hotels with a Pool
- Jacksonville Family Hotels
- Jacksonville Golf Hotels
- Jacksonville Business Hotels
- Jacksonville Hotels with Free Breakfast
- Jacksonville Hotels with a Gym
- Jacksonville Beach Hotels
- Jacksonville Pet-Friendly Hotels
- Jacksonville Luxury Hotels
- Jacksonville Resorts & Hotels with Spas
- Hotels in Las Vegas
- Hotels in New York
- Hotels in Orlando
- Hotels in Miami
- Hotels in Gatlinburg
- Hotels in Key West
- Hotels in Chicago
- Hotels in San Diego
- Hotels in Los Angeles
- Hotels in Fort Lauderdale
- Hotels in Miami Beach
- Hotels in Honolulu
- Hotels in New Orleans
- Hotels in Nashville
- Hotels in Pigeon Forge
- Hotels in Kissimmee
- Hotels in Boston
- Hotels in San Francisco
- Hotels in Atlanta
- Hotels in Panama City Beach
- Sleep Inn Jacksonville Airport
- SpringHill Suites by Marriott Jacksonville North I-95 Area
- SpringHill Suites by Marriott Jacksonville Baymeadows
- Sonesta Simply Suites Jacksonville
- Comfort Inn & Suites Jacksonville - Orange Park Near Naval Air Station
- WaterWalk Extended Stay by Wyndham Jacksonville Deerwood Pk
- La Quinta Inn & Suites by Wyndham Jacksonville Butler Blvd
- Home2 Suites by Hilton Jacksonville Airport
- Tru by Hilton Jacksonville Airport I-95
- Red Roof Inn PLUS+ Jacksonville - Southpoint
- Holiday Inn Express & Suites Jacksonville - Town Center, an IHG Hotel
- Aloft Jacksonville Airport
- Motel 6 Jacksonville, FL - Orange Park
- Baymont by Wyndham Jacksonville/Butler Blvd
- Holiday Inn Jacksonville E 295 Baymeadows, an IHG Hotel
- Quality Inn & Suites Jacksonville-Baymeadows
- Courtyard by Marriott Jacksonville Flagler Center
- SureStay Hotel by Best Western Jacksonville South
- Delta Hotels by Marriott Jacksonville Deerwood
- Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area, an IHG Hotel
- WoodSpring Suites Jacksonville - South
- Residence Inn by Marriott Jacksonville Butler Boulevard
- Hotel Indigo Jacksonville-Deerwood Park, an IHG Hotel
- Studio 6 Jacksonville, FL - Baymeadows
- Holiday Inn Express and Suites Jacksonville East, an IHG Hotel
- Tru by Hilton Jacksonville South Mandarin
- Hometown Inn & Suites Jacksonville - Butler Blvd./Southpoint
- Holiday Inn Express Jacksonville - Blount Island, an IHG Hotel
- Marriott Jacksonville
- Homewood Suites by Hilton Jacksonville-South/St. Johns Ctr.
- Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
- Aloft Jacksonville Tapestry Park
- Microtel Inn & Suites by Wyndham Jacksonville Airport
- Homewood Suites by Hilton Jacksonville Downtown-Southbank
- Courtyard by Marriott Jacksonville Butler Boulevard
- Hilton Garden Inn Jacksonville Downtown Southbank
- Extended Stay America Suites Jacksonville Riverwalk Conv Ctr
- Residence Inn By Marriott Jacksonville - Mayo Clinic Area
- Tricove Inn & Suites
- Ramada by Wyndham Jacksonville I-95 by Butler Blvd
- AC Hotel Jacksonville St Johns Town Center
- WoodSpring Suites Jacksonville Baymeadows
- Hampton Inn & Suites Jacksonville South - Bartram Park
- Residence Inn by Marriott Jacksonville Downtown
- Hampton Inn Jacksonville-I-295 East/Baymeadows
- Scottish Inn Jacksonville Downtown
- Hilton Garden Inn Jacksonville JTB/Deerwood Park
- Residence Inn by Marriott Jacksonville South/Bartram Park
- Four Points by Sheraton Jacksonville Baymeadows
- Fairfield Inn & Suites Jacksonville Airport
Most popular destinations
Hotels
Hotels in CelebrationHotels in Miami BeachHotels in St. PetersburgPet-Friendly Hotels in MiamiHotels in Lake Buena VistaCheap Hotels in Miami BeachCheap Hotels in TampaHotels in OrlandoResorts OrlandoHotels with Free Breakfast in OrlandoHotels in MiamiHotels in HollywoodHotels in Coral GablesHotels in KissimmeeHotels in St. Pete BeachCheap Hotels in OrlandoAparthotels HollywoodHotels in TampaHotels in Fort LauderdaleVillas OrlandoHotels in ClearwaterHotels in Clearwater BeachHotels with Kitchens in OrlandoVillas Lake Buena VistaCheap Hotels in Fort LauderdaleHotels near EverBank StadiumAparthotels OrlandoCheap Hotels in MiamiHotels in Jacksonville BeachHotels in Madeira Beach