Hotels in Otay Mesa West

Mon 17 Nov
Thu 20 Nov
November 2025
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December 2025

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Tonight
16 Nov - 17 Nov
Tomorrow
17 Nov - 18 Nov
Next weekend
21 Nov - 23 Nov
In two weeks
28 Nov - 30 Nov

Where to stay in Otay Mesa West?

Best Western Americana Inn

1.4 mi from Otay Mesa West
£90
includes taxes & fees
23 Nov - 24 Nov
Best Western Americana Inn

Hampton Inn & Suites Imperial Beach San Diego

3.6 mi from Otay Mesa West
£96
includes taxes & fees
24 Nov - 25 Nov
Hampton Inn & Suites Imperial Beach San Diego

Hotel Palmeras Chula Vista

4.9 mi from Otay Mesa West
£54
includes taxes & fees
17 Nov - 18 Nov
Hotel Palmeras Chula Vista

Hercor Hotel - Urban Boutique

4.2 mi from Otay Mesa West
£83
includes taxes & fees
30 Nov - 1 Dec
Hercor Hotel - Urban Boutique

La Quinta Inn by Wyndham San Diego Chula Vista

4.9 mi from Otay Mesa West
£89
includes taxes & fees
17 Nov - 18 Nov
La Quinta Inn by Wyndham San Diego Chula Vista

The Rambler

5 mi from Otay Mesa West
£79
includes taxes & fees
30 Nov - 1 Dec
The Rambler

Holiday Inn Express San Diego South - Chula Vista by IHG

4.9 mi from Otay Mesa West
£104
includes taxes & fees
30 Nov - 1 Dec
Holiday Inn Express San Diego South - Chula Vista by IHG

Best Western Plus Marina Gateway Hotel

6.5 mi from Otay Mesa West
£97
includes taxes & fees
23 Nov - 24 Nov
Best Western Plus Marina Gateway Hotel

Sun Outdoors San Diego Bay

5.1 mi from Otay Mesa West
£146
includes taxes & fees
30 Nov - 1 Dec
Sun Outdoors San Diego Bay

El Cordova Hotel on Coronado Island

10.2 mi from Otay Mesa West
£134
includes taxes & fees
20 Nov - 21 Nov
El Cordova Hotel on Coronado Island

Staypineapple, Hotel Z, Gaslamp San Diego

Gaslamp Quarter, 11 mi from Otay Mesa West
£116
includes taxes & fees
24 Nov - 25 Nov
Staypineapple, Hotel Z, Gaslamp San Diego

Hampton Inn Chula Vista Eastlake

7.6 mi from Otay Mesa West
£116
includes taxes & fees
23 Nov - 24 Nov
Hampton Inn Chula Vista Eastlake

Hard Rock Hotel San Diego

Gaslamp Quarter, 10.9 mi from Otay Mesa West
£176
includes taxes & fees
8 Dec - 9 Dec
Hard Rock Hotel San Diego

Marriott Marquis San Diego Marina

11.2 mi from Otay Mesa West
£180
includes taxes & fees
22 Nov - 23 Nov
Marriott Marquis San Diego Marina

Moxy San Diego Downtown/Gaslamp Quarter

Gaslamp Quarter, 11.2 mi from Otay Mesa West
£86
includes taxes & fees
23 Nov - 24 Nov
Moxy San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Gaslamp Quarter, 11 mi from Otay Mesa West
£119
includes taxes & fees
19 Nov - 20 Nov
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

6.8 mi from Otay Mesa West
£111
includes taxes & fees
23 Nov - 24 Nov
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Gaslamp Plaza Suites

Gaslamp Quarter, 11.3 mi from Otay Mesa West
£96
includes taxes & fees
9 Dec - 10 Dec
Gaslamp Plaza Suites

The DEXTRO Little Italy, BW Premier Collection

11.8 mi from Otay Mesa West
£84
includes taxes & fees
14 Dec - 15 Dec
The DEXTRO Little Italy, BW Premier Collection

The Sofia Hotel

11.5 mi from Otay Mesa West
£469
includes taxes & fees
4 Dec - 5 Dec
The Sofia Hotel
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Our prices for hotels in San Diego are cheapest in January
Price trends for hotels in San Diego
Pricing is based on two traveller single night rates
View properties in November
Typical weather for San Diego
November
Low crowds
High 21°C / low 14°C. Sunny most days.
View properties in November
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Monthly weather averages (˚C)

Check out reviews of Otay Mesa West hotels guests love

Sheraton San Diego Resort

Sheraton San Diego Resort

10/10 Excellent
"The room was clean and spacious. The staff was knowledgeable and helpful. "
JEFFREY 1-night trip
Posted 6 hours ago
Sheraton San Diego Resort
The Dana on Mission Bay

The Dana on Mission Bay

10/10 Excellent
"The staff was very friendly and the service was excellent"
JAIME 1-night trip
Posted 7 hours ago
The Dana on Mission Bay
Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld

10/10 Excellent
"Excellent service "
Johana 1-night trip
Posted 1 day ago
Wyndham Garden San Diego Near SeaWorld
Lafayette Hotel & Club

Lafayette Hotel & Club

10/10 Excellent
"This property is next level, unique and historic. Had a fabulous time here."
Ramona 2-night trip
Posted 1 day ago
Lafayette Hotel & Club
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

10/10 Excellent
"Room was clean and spacious "
Michael 2-night trip
Posted 2 days ago
Legacy Resort Hotel & Spa
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

10/10 Excellent
"We did not experience breakfast but everything else about the hotel was fantastic. The staff was extremely friendly and helpful. You can walk to all the restaurants and lounges."
Carla 1-night trip
Posted 2 days ago
Hard Rock Hotel San Diego
Wyndham San Diego Bayside

Wyndham San Diego Bayside

10/10 Excellent
"Older hotel. Clean. Convenient location. Friendly staff. "
Rebecca 3-night trip
Posted 2 days ago
Wyndham San Diego Bayside
Comfort Inn Sea World Area

Comfort Inn Sea World Area

10/10 Excellent
"Very clean and cozy. Nice breakfast. Good staff."
Andrey 1-night trip
Posted 2 days ago
Comfort Inn Sea World Area
The Sofia Hotel

The Sofia Hotel

10/10 Excellent
"Excellent stay all-around!"
Nalani 3-night trip
Posted 3 days ago
The Sofia Hotel

Frequently asked questions

Is Otay Mesa West expensive to stay in?
You can find great hotels from £54 in Otay Mesa West to suit a range of budgets. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".
How can I find discounted rates and deals for Otay Mesa West hotels?
Discover great deals on hotels in Otay Mesa West with Hotels.com. Sign up for free to unlock member only prices and start earning rewards. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Otay Mesa West hotels.
How can I find discounted rates and deals for Otay Mesa West hotels?
Unlocking discounted rates at hotels in Otay Mesa West couldn't be simpler. Members save up to 20% on select hotels when signed in. Silver, Gold, and Platinum members can earn additional rewards on VIP Access bookings.
Can I receive a refund if I cancel my Otay Mesa West hotel booking?
The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some Otay Mesa West hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".
Is it worth staying in Otay Mesa West?
Basing yourself in Otay Mesa West makes it easy to explore San Diego, including the areas of Zona Rio and Playas de Tijuana.
Find out more about Otay Mesa West

What's Otay Mesa West like?

If you're in search of the perfect part of town to visit, why not visit Otay Mesa West? In the larger area, you'll find top places to visit such as San Ysidro Border Crossing. Las Americas Premium Outlets and Sesame Place San Diego are a couple of places to see nearby.

How to get to Otay Mesa West

Flying to:

  • Tijuana, Baja California Norte (TIJ-General Abelardo L. Rodriguez Intl.), 5.1 mi (8.3 km) from Otay Mesa West
  • San Diego, CA (SAN-San Diego Intl.), 13.5 mi (21.8 km) from Otay Mesa West
  • San Diego, CA (MYF-Montgomery Field), 16.9 mi (27.2 km) from Otay Mesa West

Things to see and do in and around Otay Mesa West

Things to see near Otay Mesa West:

  • San Ysidro Border Crossing (2.7 mi/4.4 km away)
  • Tijuana Customs - Garita El Chaparral (2.8 mi/4.5 km away)
  • Av Revolución (3.4 mi/5.4 km away)
  • Imperial Beach (4.6 mi/7.4 km away)
  • CAS Visa USA (4.8 mi/7.7 km away)

Things to do near Otay Mesa West:

  • Las Americas Premium Outlets (2.4 mi/3.9 km away)
  • Sesame Place San Diego (2.6 mi/4.1 km away)
  • North Island Credit Union Amphitheatre (2.9 mi/4.6 km away)
  • Centro Cultural Tijuana (3.7 mi/6 km away)
  • Hidalgo Market (3.9 mi/6.3 km away)

When is the best time to visit San Diego?

  • Hottest months: August, September, July, October (average 22°C)
  • Coldest months: February, January, December, March (average 14°C)
  • Rainiest months: December, February, January, March (average 57 mm of rainfall)

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