Hotels in South San Francisco

Free cancellation options if plans change
Unlock travel rewards with One Key
Save more with Member Prices

Check prices for these dates

Tonight
13 May - 14 May
Tomorrow
14 May - 15 May
This weekend
16 May - 18 May
Next weekend
23 May - 25 May

Where to stay in South San Francisco?

Comfort Inn and Suites San Francisco Airport North
Terrace/patio

Comfort Inn and Suites San Francisco Airport North

2.5 star property
7.8 out of 10, Good, (1001)
The price is £95
includes taxes & fees
25 May - 26 May
Comfort Inn and Suites San Francisco Airport North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
trending_down

Our prices for hotels in South San Francisco are cheapest in March

See average prices and weather for all months

Price trends for hotels in South San Francisco

Pricing is based on two traveller single night rates
May
£103
Average price during May is £103
Jun
£112
Average price during June is £112
Jul
£119
Average price during July is £119
Aug
£118
Average price during August is £118
Sep
£120
Average price during September is £120
Oct
£135
Average price during October is £135
Nov
£147
Average price during November is £147
Dec
£115
Average price during December is £115
Jan
£108
Average price during January is £108
Feb
£100
Average price during February is £100
Mar
£94
Average price during March is £94
Apr
£104
Average price during April is £104
Currently viewing crowd sizes and weather for May.

May

trending_upHigh crowds
High 17°C / low 11°C. Sunny most days.
17°
weather_sun
May, High crowds, average high temperature 17 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
11°
19°
weather_sun
June, Moderate crowds, average high temperature 19 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
19°
weather_sun
July, High crowds, average high temperature 19 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
20°
weather_sun
August, High crowds, average high temperature 20 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
14°
20°
weather_sun
September, High crowds, average high temperature 20 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
15°
19°
weather_sun
October, Moderate crowds, average high temperature 19 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
14°
17°
weather_sun
November, Low crowds, average high temperature 17 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
11°
14°
weather_sun
December, Low crowds, average high temperature 14 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
14°
weather_sun
January, Low crowds, average high temperature 14 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
15°
weather_sun
February, Low crowds, average high temperature 15 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
15°
weather_sun
March, Moderate crowds, average high temperature 15 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
16°
weather_sun
April, Moderate crowds, average high temperature 16 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
10°
Monthly weather averages (˚C)
View all properties

Top neighbourhoods in South San Francisco

Default Image

The East Side

South San Francisco's The East Side neighbourhood is home to attractions, such as San Francisco Bay and San Bruno Point Park.

See properties in The East Side
The East Side

Top landmarks in South San Francisco

South San Francisco Convention Center

South San Francisco Convention Center is worth a visit, located 0.5 mi (0.8 km) from central South San Francisco. Hotels.com travellers also say the area is full of friendly people and that it has lots of nice beaches. It's also full of great shops and restaurants, so you can spend the afternoon having a wander.

See properties in South San Francisco Convention Center
South San Francisco Convention Center

Learn more about South San Francisco

South San Francisco is well known for its castle, while top attractions include San Francisco Bay. Visitors to this family-friendly city speak highly of the restaurants whereas sights include South San Francisco Convention Center and Santa Cruz Mountains.

See all hotels in South San Francisco

Check out reviews of South San Francisco hotels guests love

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf

10/10 Excellent
"Great hotel, great location, exceptionally comfortable beds"
Gail 7-night trip
Posted 11 hours ago
Hotel Caza Fisherman's Wharf
A tranquil hotel pool encircled by beautiful arches

Summer Getaway Sale

Sign in to save 25%+ on selected hotels, and earn 50% more rewards on all properties. Book by 26 May and travel by 30 Sep 2025. See terms*
Sign in or join for free

Frequently asked questions

What hotels do travellers recommend in South San Francisco?
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront, Hampton Inn San Francisco Airport and Home2 Suites by Hilton San Francisco Airport North are all properties that our guests really like.
Where can I get free parking with my stay in South San Francisco?
Park your car for free at Americana Inn.
Can I book a refundable accommodation option in South San Francisco?
If you want the flexibility to change your plans to South San Francisco, most hotels offer refundable* rates that you can book. You can find these properties by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay with my pet in South San Francisco?
Your animal companion is welcome at these pet-friendly hotels: DoubleTree by Hilton San Francisco South Airport Blvd, La Quinta Inn & Suites by Wyndham San Francisco Airport N and Home2 Suites by Hilton San Francisco Airport North. There are 22 options on our site to choose from.
Which South San Francisco hotels do travellers like for their great location?
Travellers like DoubleTree by Hilton San Francisco South Airport Blvd for its great location.
Where can I stay in South San Francisco if I want a holiday rental instead of a hotel?
If you want to find a good alternative to a hotel, browse our selection of 64 holiday homes. In addition, you can choose from 10 apartments.
Where can I stay if I'm travelling to South San Francisco with my family?
Parents travelling with children may want to consider La Quinta Inn & Suites by Wyndham San Francisco Airport N, Embassy Suites San Francisco Airport - South San Francisco and Best Western Plus Grosvenor Airport Hotel. You can also see 8 available options on our site.
Where should I stay in South San Francisco for a holiday with my partner?
Inn At Oyster Point, La Quinta Inn & Suites by Wyndham San Francisco Airport N and Comfort Inn and Suites San Francisco Airport North are great options for a romantic getaway. You can also see all 8 options on our site.
Where should I stay in South San Francisco if I want a luxury hotel?
An option for a luxury stay is DoubleTree by Hilton San Francisco South Airport Blvd. Additionally, view all 9 options on our site.
What will the weather in South San Francisco be like during my visit?
The warmest months in South San Francisco are usually September and August, with an average temperature of 17°C. February and January are the chilliest months, when the average temperature is 11°C. The rainiest months are December and January.
Why should I book my South San Francisco hotel with Hotels.com?
There are lots of reasons to book your South San Francisco trip with us: our free cancellations on selected hotels* gives you flexibility, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.

Terms and conditions

*Book by 26/5/2025 11:59pm in hotel property local time. Stay between 17/4/2025–30/9/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

One Key members save more, as compared to non-members shopping on Hotels.com. OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia® and Vrbo®.